Opioid dependence found to permanently change brains of rats

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, published Jan. 14, 2020 in PNAS, researchers at University of California San Diego School of Medicine found that opioid dependence produced permanent changes in the brains of rats.

Controlled Substances Market Growing Popularity and Emerging Trends 2020 to 2025

QY Research offers its latest report on the global Controlled Substances market that includes comprehensive analysis on a range of subjects such as competition, segmentation, regional expansion, and market dynamics.

The report is a brilliant presentation of critical dynamics, regional growth, competition, and other important aspects of the global Controlled Substances market. It provides accurate market figures and statistics including CAGR, revenue, volume, consumption, production, market shares, price, and gross margin. Each regional market studied in the report is carefully analyzed to explore key opportunities and business prospects they are expected to offer in the near future.

The authors of the report profile some of the leading names of the global Controlled Substances market on the basis of various factors. This equips players with crucial information and data to improve their business tactics and ensure a strong foothold in the global Controlled Substances market.

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What Is CBG And Is It Legal?

Like CBD, CBG is among the 100+ molecules in the cannabis plant. Unlike CBD, the legal status of CBG products may be less problematic.

Looking back, 2019 was the year of cannabidiol (CBD) in the cannabis industry. CBD continued to make its way into countless consumer products, from sodas to sports bras. The CBD craze was a long time coming: we began covering that cannabinoid back in 2015, when industry began promoting CBD products in earnest and the FDA fired off warning letters (a time-honored tradition at this point) telling people to stop making health claims, and to stop selling this stuff altogether

Another cannabinoid has begun getting a lot of buzz inside the cannabis industry, much like CBD before it. That cannabinoid is CBG (cannabigerol). Like CBD, CBG is among the 100+ molecules in the cannabis plant. From a scientific perspective, CBG is unique for the “precursor” role it plays in synthesizing other cannabinoids–including THC and CBD–and in synthesizing the overall chemical composition of the plant. From a regulatory perspective, the legal status of CBG products may be less problematic than CBD products.

What You Need to Know About the Healing Benefits of Marijuana’s CBG:

Although THC and CBD are two commonly consumed cannabinoids, CBG is gaining more popularity and attention due to its medicinal value.

Cannabis is an extremely complex plant, and it contains many more cannabinoids than just THC and CBD. How many cannabinoids do you think this plant contains? So far, more than 60 cannabinoid compounds have been discovered, and cannabigerol (CBG) is one of them.

CBG is a non-psychoactive cannabinoid that can help treat multiple medical conditions, diseases, and illnesses. Although THC and CBD are two commonly consumed cannabinoids, CBG is gaining more popularity and attention due to its medicinal value.

CBG Medicinal Properties & Benefits

Before learning about CBG’s medicinal properties, it’s essential to know that CBG is non-psychoactive, non-impairing, and non-intoxicating. CBG can act on the body’s central nervous system without creating a psycho-active high. Therefore, users don’t have to worry about feeling high after consumption. Not only does CBG contain anti-bacterial, anti-microbial, and anti-septic properties, but it also holds efficacy in battling against MRSA (Methicillin-resistant Staphylococcus aureus). Specifically, in a 2008 study, CBG demonstrated its effectiveness against MRSA.
In addition, one 2009 review article found that CBG and other cannabinoids can slow the progression and growth of various tumors and cancer cells. Due to CBG’s ability to inhibit the growth of cancer cells and tumors, this cannabinoid shows a significant promise in helping treat different forms of cancer. Similarly, in recent years, CBG was found to be an extremely active neuroprotectant, especially regarding Huntington’s Disease. It has been discovered that CBG can help protect neurons, which can be useful in treating many neurodegenerative diseases.

CBG’s Mental Health Benefits

Now, what are CBG’s non-physical benefits? For starters, a 2016 report showed that CBG could be an alternative form of treatment for anxiety and depression. Thus far, CBG’s anti-anxiety properties have been revealed through different research findings, but more research needs to be done. Additionally, since CBG can block serotonin receptors, this suggests a potential role for this cannabinoid helping treat depression.
CBG also possesses the ability to inhibit the uptake of the brain’s GABA. GABA is often referred to as an amino acid that acts as a neurotransmitter within the central nervous system and also calms the system down. GABA can block nerve impulses, and when GABA is inhibited, it can result in lessened anxiety and muscle tension. Thus, it’s believed that CBG can provide anti-anxiety and potentially anti-depressant effects.

Additional Medicinal Properties of CBG:

Aside from the many medical benefits mentioned above, CBG even contains analgesic properties, which can help treat numerous diseases and illnesses. Now, rewind over a decade to when one 2007 study was conducted, which revealed that CBG inhibited keratinocyte proliferation. This suggests a significant role for CBG aiding in the treatment of skin disorders including psoriasis. In general, though, CBG can simplify the making of natural skin-moisturizers, thus, this cannabinoid could be used to combat dry skin and other skin disorders.
Overall, not only does CBG contain a plethora of medicinal properties, but it can also have a positive impact on people’s lives. Whether you currently experience health issues or not, this cannabinoid shows a significant potential in helping treat different conditions, diseases, and illnesses.